Viruses discovered a century ago may be our best defense against a threat that could kill 10 million people a year by 2050

Antibiotic resistance — the phenomenon in which bacteria stop responding to certain antibiotics — is a growing threat around the world. It’s expected to kill 10 million people annually by 2050. And it hasn’t been easy to develop new drugs in order to stay ahead of the problem. Many major pharmaceutical companies have stopped developing new…

Addressing superbug resistance with phage therapy

International research involving a Monash biologist shows that bacteriophage therapy – a process whereby bacterial viruses attack and destroy specific strains of bacteria – can be used successfully to treat systemic, multidrug resistant bacterial infections. The latest research, published in Antimicrobial Agents & Chemotherapeutics has wide implications for antibiotic resistance, which the World Health Organization…

Findings of Novel Phage Therapy That Saved Professor’s Life Published

Writing in the September issue of the journal Antimicrobial Agents and Chemotherapy, a large and diverse team of researchers has published the full details of the dramatic, experimental and ultimately successful effort to save the life of a patient infected with a multidrug-resistant bacterium. The findings describe a potentially powerful new tool — bacteriophages https://en.wikipedia.org/wiki/Bacteriophage — for addressing…

Phage therapy in a 16 year old boy with Netherton’s Syndrome

Netherton’s Syndrome (NS) is a rare autosomal recessive disorder, characterized by a classical triad of clinical features, including congenital ichthyosiform erythroderma, trichorrhexis invaginata, and atopic diathesis coupled with frequent bacterial infections. The genetic basis for the disease has been recently identified with mutations in gene SPINK5 which is involved in the regulation of formation of…

Alarming rise in children’s resistance to antibiotics

For every 100 hospitalised pediatric patients across India who may need a common antibiotic called ampicillin to fight infections, chances are it won’t help 95 of them. In 75% of hospitalised children, especially those younger than one month old, another common antibiotic, gentamycin, may not work.The reason, according a recent study by pediatricians of Apollo…

Young Edmonds boy MRSA free after unusual treatment

EDMONDS, Wash. — A local family celebrating after getting a clean bill of health for their 4-year old son. He battled a rare congenital defect and a life threatening infection. They came across a KOMO News story on a treatment called phage therapy and say phage made all the difference. When 75 people gather at…

Houston superbug may be a warning of nightmares to come

A dangerous strain of antibiotic-resistant bacteria is far more common in Houston than anyone knew and shows signs it can spread prolifically, researchers reported Tuesday. It’s a specific strain of a bacteria known as Klebsiella pneumoniae. The superbug is showing a special talent for picking up genes that give it the ability to resist a…