Patient education: Cystic fibrosis (CF) What is cystic fibrosis? — Cystic fibrosis is a disease of exocrine gland function that involves multiple organ systems. It is an autosomal recessive disorder caused by an abnormal gene called – cystic fibrosis transmembrane conductance regulator gene (CFTR). The symptoms are associated with the production of hyper viscous…
Patient education: Irritable bowel syndrome What is irritable bowel syndrome? – Irritable bowel syndrome, or “IBS,” is a condition that causes belly pain and problems with bowel movements. Some people with the condition have frequent, watery bowel movements (diarrhea). Others do not have enough bowel movements (constipation). Some patients switch back and forth between…
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The research could pave the way for bacteriophage treatments for other diseases. We are one step closer to seeing a new kind of treatment to combat inflammatory bowel disease (IBD). On February 15, the U.S. Food and Drug Administration (FDA) gave its seal of approval to a new Phase 1/2 clinical trial in humans…
On the evening of Nov. 7, Steffanie Strathdee sent out a cryptic tweet: “#Phage researchers! I am working with a team to get Burkholderia cepacia phages to treat a 25 y old woman with CF whose infection has failed all #antibiotics. We need lytic non-lysogenic phage URGENTLY to find suitable phage matches. Email if you…
Antibiotic resistance — the phenomenon in which bacteria stop responding to certain antibiotics — is a growing threat around the world. It’s expected to kill 10 million people annually by 2050. And it hasn’t been easy to develop new drugs in order to stay ahead of the problem. Many major pharmaceutical companies have stopped developing new…
As overused antibiotics become less and less effective, a tantalising discovery may revolutionise healthcare Steffanie Strathdee feared the worst when husband Tom Patterson comatosed Husband of 13 years lay in a deep coma, the victim of an aggressive superbug His heart, lungs and major organs were all shutting down with little hope left Apparently miraculous…
International research involving a Monash biologist shows that bacteriophage therapy – a process whereby bacterial viruses attack and destroy specific strains of bacteria – can be used successfully to treat systemic, multidrug resistant bacterial infections. The latest research, published in Antimicrobial Agents & Chemotherapeutics has wide implications for antibiotic resistance, which the World Health Organization…
Writing in the September issue of the journal Antimicrobial Agents and Chemotherapy, a large and diverse team of researchers has published the full details of the dramatic, experimental and ultimately successful effort to save the life of a patient infected with a multidrug-resistant bacterium. The findings describe a potentially powerful new tool — bacteriophages https://en.wikipedia.org/wiki/Bacteriophage — for addressing…