Writing in the September issue of the journal Antimicrobial Agents and Chemotherapy, a large and diverse team of researchers has published the full details of the dramatic, experimental and ultimately successful effort to save the life of a patient infected with a multidrug-resistant bacterium. The findings describe a potentially powerful new tool — bacteriophages https://en.wikipedia.org/wiki/Bacteriophage — for addressing…
Netherton’s Syndrome (NS) is a rare autosomal recessive disorder, characterized by a classical triad of clinical features, including congenital ichthyosiform erythroderma, trichorrhexis invaginata, and atopic diathesis coupled with frequent bacterial infections. The genetic basis for the disease has been recently identified with mutations in gene SPINK5 which is involved in the regulation of formation of…
For every 100 hospitalised pediatric patients across India who may need a common antibiotic called ampicillin to fight infections, chances are it won’t help 95 of them. In 75% of hospitalised children, especially those younger than one month old, another common antibiotic, gentamycin, may not work.The reason, according a recent study by pediatricians of Apollo…
EDMONDS, Wash. — A local family celebrating after getting a clean bill of health for their 4-year old son. He battled a rare congenital defect and a life threatening infection. They came across a KOMO News story on a treatment called phage therapy and say phage made all the difference. When 75 people gather at…
(CNN)The number of cases of an emerging and often multidrug-resistant fungus in the United States has grown from seven to 122 over the past nine months, according to a field report in the Morbidity and Mortality Weekly Report issued Thursday by the US Centers for Disease Control and Prevention. The fungus, Candida auris, can…
A dangerous strain of antibiotic-resistant bacteria is far more common in Houston than anyone knew and shows signs it can spread prolifically, researchers reported Tuesday. It’s a specific strain of a bacteria known as Klebsiella pneumoniae. The superbug is showing a special talent for picking up genes that give it the ability to resist a…
Abstract In this retrospective descriptive study we focus on cases of three patients who underwent phage therapy procedures at Eliava Phage Therapy Center (EPTC) in Tbilisi, Georgia. Patients with chronic infectious diseases related to Pseudomonas aeruginosa (two patients, lower respiratory tract infection (LRTI)) and Klebsiella pneumoniae (one patient, urinary tract infection (UTI)) are among those very few EPTC patients…
As Human Phage Therapy Day (April 27) approaches, a collaborative team of researchers led by investigators at the University of California San Diego (UCSD) School of Medicine is preparing to present data about the successful treatment of a patient near death from a multidrug-resistant bacterium using an experimental therapy involving bacteriophages. The scientists and clinicians…
The FINANCIAL — Scientists from the University of Liverpool’s Institute of Infection and Global Health have shown that phage therapy could offer a safe and effective alternative to antibitotics in the treatment of Cystic Fibrosis lung infections. Chronic lung infections caused by the bacterium Pseudomonas aeruginosa are becoming increasingly difficult to treat due to antimicrobial…
Phage therapy has hit newsstands once again! People who have cystic fibrosis and other chronic lung conditions suffer from frequent lung infections, often caused by Pseudomonas aeruginosa. Now, researchers from the University of Liverpool report that phage therapy could be a safe (and effective!) alternative to antibiotics for treating these patients. Phage are viruses that…